ACE inhibitors for patients with vascular disease without left ventricular dysfunction--may they rest in PEACE?
نویسنده
چکیده
s since January 1975, a full-text search capacity, and a personal archive for saving articles and search results of interest. All articles can be printed in a format that is virtually identical to that of the typeset pages. Beginning six months after publication, the full text of all Original Articles and Special Articles is available free to nonsubscribers who have completed a brief registration. Copyright © 2004 Massachusetts Medical Society. All rights reserved. Downloaded from www.nejm.org at UNIV MINN / BIOMED LIB COPY 1 on November 14, 2004 .
منابع مشابه
Angiotensin-converting enzyme inhibitors.
ACE inhibitors have achieved widespread usage in the treatment of cardiovascular and renal disease. ACE inhibitors alter the balance between the vasoconstrictive, salt-retentive, and hypertrophic properties of angiotensin II (Ang II) and the vasodilatory and natriuretic properties of bradykinin and alter the metabolism of a number of other vasoactive substances. ACE inhibitors differ in the che...
متن کاملAngiotensin-converting-enzyme inhibition in stable coronary artery disease.
BACKGROUND Angiotensin-converting-enzyme (ACE) inhibitors are effective in reducing the risk of heart failure, myocardial infarction, and death from cardiovascular causes in patients with left ventricular systolic dysfunction or heart failure. ACE inhibitors have also been shown to reduce atherosclerotic complications in patients who have vascular disease without heart failure. METHODS In the...
متن کاملAngiotensin-converting enzyme inhibitors in patients with coronary atherosclerosis.
Activation of the renin-angiotensin-aldosterone system has been shown to be an independent risk factor for myocardial infarction (MI). The importance of this risk factor has been confirmed by the finding that patients with a DD genotype for the angiotensin-converting enzyme (ACE) gene, which is associated with increased serum ACE levels, have a higher incidence of MI than do patients without th...
متن کاملShould an angiotensin-converting enzyme inhibitor be standard therapy for patients with atherosclerotic disease?
Angiotensin-converting enzyme (ACE) inhibitors appear to possess unique cardioprotective benefits, even when used in patients without high blood pressure or left ventricular dysfunction (the traditional indications for ACE inhibitor therapy). The ACE inhibitors improve endothelial function and regress both left ventricular hypertrophy and arterial mass better than other antihypertensive agents ...
متن کاملBlood pressure-lowering for secondary prevention of stroke: ACE inhibition is the key.
Angiotensin-converting enzyme (ACE) inhibitors undoubtedly represent one of the major advances in cardiovascular therapeutics over the past 20 years. Having been originally derived from the venom of the Brazilian arboreal viper Bothrops jararaca, captopril and subsequent ACE inhibitors are currently well-established agents for the treatment of patients with hypertension, heart failure, and left...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The New England journal of medicine
دوره 351 20 شماره
صفحات -
تاریخ انتشار 2004